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Chen-Kai JIANG, De-Jiang NI, Ming-Zhe YAO, Jian-Qiang MA, Liang CHEN
Frontiers of Agricultural Science and Engineering Pages 215-230 doi: 10.15302/J-FASE-2021382
Keywords: harvest season metabolites tea shoots transcriptomics untargeted metabolomics
Progress in NMR-based metabolomics of
Qifang PAN,Jingya ZHAO,Yuliang WANG,Kexuan TANG
Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3, Pages 195-204 doi: 10.15302/J-FASE-2015063
Keywords: Catharanthus roseus monoterpenoid indole alkaloids NMR metabolomics
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 1, doi: 10.1007/s11783-023-1604-5
● Metabolomic temporal profiling of cells exposed to xenobiotics.
Keywords: Metabolomics BPA MCF-7 Temporal profiling Metabolic adaption Dysregulation correlation
Metabolomics in human type 2 diabetes research
Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 4-13 doi: 10.1007/s11684-013-0248-4
Keywords: metabolomics type 2 diabetes metabolic pathway mass spectrometry nuclear magnetic resonance (NMR)
Sepsis biomarkers: an omics perspective
Xiao Liu, Hui Ren, Daizhi Peng
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 58-67 doi: 10.1007/s11684-014-0318-2
Keywords: sepsis biomarker genomics transcriptomics proteomics metabolomics
Heng Fang, Aihua Zhang, Xiaohang Zhou, Jingbo Yu, Qi Song, Xijun Wang
Frontiers of Medicine 2020, Volume 14, Issue 5, Pages 651-663 doi: 10.1007/s11684-019-0709-5
Keywords: metabolomics liquid chromatography-mass spectrometry metabolites metabolic pathways
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1628-x
● Metabolome can distinguish pregnant women exposure to PFOA at different degrees.
Keywords: Perfluorooctanoic acid Exposure Pregnant women Metabolomic GSH Microbiota metabolism
Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma
Frontiers of Medicine doi: 10.1007/s11684-023-1020-z
Keywords: RLPS proteomics metabolomics lipidomics metabolism
Frontiers of Medicine doi: 10.1007/s11684-023-1022-x
Keywords: acute promyelocytic leukemia plasma proteomics plasma metabolomics cross-sectional correlation network
Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12, Pages 1751-1760 doi: 10.1007/s11705-022-2211-x
Keywords: ARTP mutagenesis Bacillus licheniformis poly-γ-glutamic acid metabolomics
Ai-Hua Zhang, Hui Sun, Guang-Li Yan, Ying Han, Qi-Qi Zhao, Xi-Jun Wang
Engineering 2019, Volume 5, Issue 1, Pages 60-68 doi: 10.1016/j.eng.2018.11.008
Keywords: Chinmedomics Serum pharmacochemistry of TCM Efficacy Metabolomics Syndrome Biomarkers Quality markers
Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Article
Bingbing Li, Ying Hong, Yu Gu, Shengjie Ye, Kaili Hu, Jian Yao, Kan Ding, Aihua Zhao, Wei Jia, Houkai Li
Engineering 2022, Volume 9, Issue 2, Pages 111-122 doi: 10.1016/j.eng.2020.05.023
Keywords: Astragalus polysaccharides (APS) Functional metabolomics 2-Hydroxybutyric acid Obesity
Deeper Chemical Perceptions for Better Traditional Chinese Medicine Standards Review
Jin-Jun Hou,Jian-Qing Zhang,Chang-Liang Yao,Rudolf Bauer,Ikhlas A. Khan,Wan-Ying Wu,De-an Guo
Engineering 2019, Volume 5, Issue 1, Pages 83-97 doi: 10.1016/j.eng.2018.12.005
Traditional Chinese medicines (TCMs), a complex system of natural resources with many diverse components, are widely used as approved medicinal agents in China. Quality control of TCMs is a huge challenge for the government and for testing institutes and is associated with numerous scientific issues. Among these considerations include the following questions: How many components are in TCMs? How can the multiple components in TCMs be comprehensively delineated and subsequently characterized? What is the level and range of these (active) metabolites within these multiple-component TCMs, in order to recommend standards? and What are the qualities required for a marker constituent to be selected, and from a practical perspective, how can these components be assessed with low cost and in a short time? All of these factors require significant and deep thinking in order to understand the individualistic chemistry of TCM in order to develop enhanced TCM quality standards for improved and consistent patient care. In this review, the latest exploratory research in TCM chemistry analytical techniques and methods is summarized in order to begin to develop responses to these scientific issues. Advances in these methods have included multidimensional separation for liquid chromatography–high-resolution mass spectrometry (LC–HRMS), smart triggering data-dependent acquisition of LC–HRMS, target analysis with liquid chromatography–mass spectrometry (LC–MS), supercritical fluid chromatography, and data mining of large mass spectrometry (MS) datasets. In addition, two quality strategies have been introduced in order to save reference standards and the analysis time for a TCM quality standard, including the application of the single standard to determine multi-components (SSDMC) and monomethodheterotrait matrix methods. Finally, a series of future improvements for analytical methods for TCMs are proposed.
Keywords: Traditional Chinese medicine Liquid chromatography Mass spectrometry Data-dependent acquisition Chemometrics Untargeted
Yingdan Zhang, Na Liu, Wei Wang, Jianteng Sun, Lizhong Zhu
Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1282-5
Keywords: Nano-TiO2 Rice Photosynthesis Metabolomics Energy storage
Chunyu Li, Ming Niu, Zhaofang Bai, Congen Zhang, Yanling Zhao, Ruiyu Li, Can Tu, Huifang Li, Jing Jing, Yakun Meng, Zhijie Ma, Wuwen Feng, Jinfa Tang, Yun Zhu, Jinjie Li, Xiaoya Shang, Zhengsheng Zou, Xiaohe Xiao, Jiabo Wang
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 253-265 doi: 10.1007/s11684-017-0508-9
Keywords: Polygonum multiflorum idiosyncratic hepatotoxicity metabolomics stilbene cis-transisomerization
Title Author Date Type Operation
METABOLIC AND TRANSCRIPTOME ANALYSIS REVEALS METABOLITE VARIATION AND FLAVONOID REGULATORY NETWORKS IN FRESH SHOOTS OF TEA (
Chen-Kai JIANG, De-Jiang NI, Ming-Zhe YAO, Jian-Qiang MA, Liang CHEN
Journal Article
Progress in NMR-based metabolomics of
Qifang PAN,Jingya ZHAO,Yuliang WANG,Kexuan TANG
Journal Article
Time-dependent metabolomics uncover dynamic metabolic adaptions in MCF-7 cells exposed to bisphenol A
Journal Article
Metabolomics in human type 2 diabetes research
Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia
Journal Article
High-throughput metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang syndrome
Heng Fang, Aihua Zhang, Xiaohang Zhou, Jingbo Yu, Qi Song, Xijun Wang
Journal Article
Untargeted metabolomic analysis of pregnant women exposure to perfluorooctanoic acid at different degrees
Journal Article
Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma
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Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acute promyelocytic leukemia
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Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric and room temperature plasma mutagenesis
Journal Article
Chinmedomics: A Powerful Approach Integrating Metabolomics with Serum Pharmacochemistry to Evaluate the
Ai-Hua Zhang, Hui Sun, Guang-Li Yan, Ying Han, Qi-Qi Zhao, Xi-Jun Wang
Journal Article
Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through
Bingbing Li, Ying Hong, Yu Gu, Shengjie Ye, Kaili Hu, Jian Yao, Kan Ding, Aihua Zhao, Wei Jia, Houkai Li
Journal Article
Deeper Chemical Perceptions for Better Traditional Chinese Medicine Standards
Jin-Jun Hou,Jian-Qing Zhang,Chang-Liang Yao,Rudolf Bauer,Ikhlas A. Khan,Wan-Ying Wu,De-an Guo
Journal Article
Photosynthesis and related metabolic mechanism of promoted rice (Oryza sativa L.) growth by TiO2 nanoparticles
Yingdan Zhang, Na Liu, Wei Wang, Jianteng Sun, Lizhong Zhu
Journal Article
Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum
Chunyu Li, Ming Niu, Zhaofang Bai, Congen Zhang, Yanling Zhao, Ruiyu Li, Can Tu, Huifang Li, Jing Jing, Yakun Meng, Zhijie Ma, Wuwen Feng, Jinfa Tang, Yun Zhu, Jinjie Li, Xiaoya Shang, Zhengsheng Zou, Xiaohe Xiao, Jiabo Wang
Journal Article